1364511-86-3Relevant academic research and scientific papers
Pd-catalysed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation
Zhong, Hongban,Yang, Dan,Wang, Songqing,Huang, Jianhui
supporting information; experimental part, p. 3236 - 3238 (2012/04/11)
An atom economical synthesis of isoquinolinones and analogues via ligand-free Pd-catalysed C-H and N-H double activation has been developed. A series of isoquinolinones were obtained in good to excellent yields. Good regioselectivities were also observed during the activation reactions with unsymmetrical alkynes. A practical one-pot procedure for the preparation of N-H isoquinolinones is also described. The Royal Society of Chemistry 2012.
