1364663-35-3

Usage

Uses

Used in Pharmaceutical Research:
6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine is used as a reagent for protecting the amino group of pyrimidines during chemical reactions, facilitating the development of new pharmaceuticals with enhanced properties and therapeutic effects.
Used in Organic Synthesis:
In the field of organic synthesis, 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine is utilized as a key intermediate for the synthesis of complex organic molecules. Its ability to protect the amino group allows for the creation of diverse pyrimidine-based compounds with specific functionalities.
Used in Chemical Reactions:
6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine is employed as a protecting agent in chemical reactions to prevent unwanted side reactions involving the amino group. This ensures the selective formation of desired products and improves the overall yield and purity of the synthesized compounds.
Overall, 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine plays a crucial role in the advancement of organic chemistry and pharmaceutical development, offering unique reactivity and selectivity for the synthesis of novel compounds with potential applications in various industries.

Upstream product

• 1365992-75-1 (6-azidopyrimidin-4-yl)-bis-carbamic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 354112-08-6 tert-butyl N-tert-butoxycarbonyl-N-(6-chloropyrimidin-4-yl)carbamate 

Downstream Products

• 1378040-48-2 {6-[2-(2,6-dichlorophenyl)-7-methyl-2H-pyrazolo[4,3-c]pyridin-4-ylamino]-pyrimidin-4-yl}-carbamic acid tert-butyl ester 
• 1378040-47-1 {6-[2-(2,6-dichlorophenyl)-7-methyl-2H-pyrazolo[4,3-c]pyridin-4-ylamino]-pyrimidin-4-yl}-bis-carbamic acid tert-butyl ester 
• 1378040-12-0 {6-[7-chloro-2-(2,6-dichloro-4-cyanophenyl)-2H-pyrazolo[4,3-c]pyridin-4-ylamino]-pyrimidin-4-yl}-bis-carbamic acid tert-butyl ester 
• 1365992-54-6 C₂₆H₂₅ClF₂N₆O₄S 
• 1365992-35-3 C₃₁H₃₅Cl₂N₇O₆S 

Relevant academic research and scientific papers

PYRAZOLOPYRIDINES AND PYRAZOLOPYRIDINES AND THEIR USE AS TYK2 INHIBITORS

The invention provides compounds of Formula (I), stereoisomers or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula (I) and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of using the compound or composition in therapy, as TYK2 Kinase inhibitors.

AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE

Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of 5 manufacturing a compound of Formula I