136476-26-1

Basic information

• Product Name: Benzaldehyde, 2-[1-(trifluoromethyl)ethenyl]-
• CAS NO: 136476-26-1
• Molecular Formula: C10H7F3O
• Molecular Weight: 200.16
• Mol File: 136476-26-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-[1-(trifluoromethyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-[1-(trifluoromethyl)ethenyl]-(136476-26-1)
• EPA Substance Registry System: Benzaldehyde, 2-[1-(trifluoromethyl)ethenyl]-(136476-26-1)

Safety Data

• Hazardous Substances Data: 136476-26-1(Hazardous Substances Data)

Upstream product

• 1601477-00-2 4-methyl-N'-(1,1,1-trifluoropropan-2-ylidene)benzenesulfonohydrazide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 26260-02-6 2-iodobenzaldehyde 
• 357274-85-2 α-(trifluoromethyl)ethenyl boronic acid 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 40138-16-7 2-formylbenzene boronic acid 

Downstream Products

• 1145778-08-0 1-[2-(3,3,3-trifluoroprop-1-en-2-yl)phenyl]pentan-l-ol 
• 1145778-09-1 phenyl[2-(3,3,3-trifluoroprop-1-en-2-yl)phenyl]methanol 

Relevant articles and documents

Asymmetric Allylation/RCM-Mediated Synthesis of Fluorinated Benzo-Fused Bicyclic Homoallylic Amines As Dihydronaphthalene Derivatives

Enantiomerically enriched fluorinated benzo-fused bicyclic homoallylic amines have been synthesized through an asymmetric allylation/ring closing metathesis (RCM) sequence. This sequence has been carried out using α-trifluoromethylstyrene derivatives as key intermediates, synthesized by microwave radiation. The great deactivating effect exerted by such substituents has been brought to light by a comparative study.

Hydroacylation of 2-vinyl benzaldehyde systems: An efficient method for the synthesis of chiral 3-substituted indanones

Asymmetric rhodium-catalyzed hydroacylation has been utilized in the synthesis of 3-substituted indanones with high conversions and enantioselectivity. The hydroacylation reaction of 2-vinyl benzaldehyde had been previously reported to give a low yield of indanone and an unidentified product. We have identified this compound as a dimer of the starting material. Substitution at the α-position of the 2-vinyl benzaldehyde substrates blocks the competitive dimerization reaction and allows the reaction to proceed with yields generally greater than 90%. Utilization of BINAP as a chiral ligand results in good chemical yields and enantioselectivity greater than 95% in most cases. Copyright