136491-77-5

Upstream product

• 135716-18-6 (4aS,5S,6S,8aS)-5-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3,4-dihydroxy-6-methyl-octahydro-naphthalen-2-one 
• 135734-44-0 (4aS,7S,8S,8aS)-8-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-7-methyl-octahydro-isochromen-3-one 
• 135716-17-5 (4aR,5S,6S,8aS)-5-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-6-methyl-4a,5,6,7,8,8a-hexahydro-1H-naphthalen-2-one 
• 136491-76-4 (4aS,7S,8S,8aS)-8-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-7-methyl-octahydro-isochromen-3-ol 
• 135716-19-7 [(1S,2S,3S,6S)-6-Allyl-2-(2-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-cyclohexyl]-methanol 
• 135716-23-3 [(1S,2S,3S,6R)-2-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-6-propyl-cyclohexyl]-methanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 135716-24-4 (2-{(4S,6R)-6-[2-((1S,2S,3R,6S)-2-Azidomethyl-6-methyl-3-propyl-cyclohexyl)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethoxy)-tert-butyl-diphenyl-silane 
• 135716-27-7 N-{(1S,2S,3S,6R)-2-[2-((2R,4R)-4-Hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3-methyl-6-propyl-cyclohexylmethyl}-2,2-dimethyl-butyramide 
• 135716-25-5 N-((1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-Hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl)-2,2-dimethyl-butyramide 
• 136491-82-2 [(4R,6R)-6-(2-{(1S,2S,3R,6S)-2-[(2,2-Dimethyl-butyrylamino)-methyl]-6-methyl-3-propyl-cyclohexyl}-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-acetic acid 
• 136598-09-9 [(4R,6R)-6-(2-{(1S,2S,3R,6S)-2-[(2,2-Dimethyl-butyrylamino)-methyl]-6-methyl-3-propyl-cyclohexyl}-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-acetic acid methyl ester 
• 136491-78-6 C-[(1S,2S,3S,6R)-2-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-6-propyl-cyclohexyl]-methylamine 
• 135734-45-1 N-[(1S,2S,3S,6R)-2-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-6-propyl-cyclohexylmethyl]-2,2-dimethyl-butyramide 
• 135716-30-2 [1S-[1α(βS*,δS*),2β,3α,6α]]-2-[[(2,2-Dimethyl-1-oxobutyl)amino]methyl]-β,δ-dihydroxy-6-methyl-3-propylcyclohexaneheptanoic acid, monolithium salt 

Relevant academic research and scientific papers

Synthetic transformations of the mevinic acid nucleus: Preparation of a monocyclic analogue of compactin

The synthetic transformation of pravastatin into a fully functional, monocyclic analogue of compactin via a multistep sequence is described.