136495-45-9Relevant academic research and scientific papers
Synthesis of 2-Bis(trifluoromethyl)hydroxymethyl Substituted Cyclic Amines through Novel Intramolecular Substitution of an Arylsulfonyl Group
Taguchi, Takeo,Suda, Yoshimitsu,Hamochi, Masahiko,Fujino, Yasuhiro,Iitaka, Yoichi
, p. 1425 - 1428 (2007/10/02)
ω-Amino-1,1-bis(trifluoromethyl)-2-sulfonyl-1-pentanol or -hexanol provided the corresponding pyrrolidine or piperidine having BTHM group at the 2-position via intermediary epoxide by treating with NaOH in the presence of phase-transfer catalyst.
