1365052-57-8

Basic information

• Product Name: C₁₉H₁₇BrN₂O₂
• Synonyms: C₁₉H₁₇BrN₂O₂
• CAS NO: 1365052-57-8
• Molecular Weight: 385.26
• Mol File: 1365052-57-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₇BrN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₇BrN₂O₂(1365052-57-8)
• EPA Substance Registry System: C₁₉H₁₇BrN₂O₂(1365052-57-8)

Safety Data

• Hazardous Substances Data: 1365052-57-8(Hazardous Substances Data)

Upstream product

• 1761-61-1 5-bromosalicyclaldehyde 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 636992-53-5 1-(3-amino-5-bromo-benzofuran-2-yl)-ethanone 
• 40530-18-5 5-bromo-2-hydroxybenzonitrile 

Downstream Products

• 1365052-67-0 C₁₉H₁₉BrN₄O 
• 1365052-77-2 C₂₁H₂₀BrClN₄O₂ 

Relevant articles and documents

Synthesis and biological evaluation of some novel benzofuranpyridine derivatives

5-Bromo-3-amino-2-acetyl benzofuran 3 was prepared by the reaction of 5- bromosalicylonitrile 2 with chloroacetone in dry acetone in presence of anhydrous potassium carbonate to maintain basic condition. The Claisen-Schmidt condensation of compound 3 with various substituted aromatic aldehydes in presence of strong base in absolute ethanol gave 5-bromo-3-amino-2-arylidine acetyl benzofuran 4a-f in good yields. The compounds 4a-f upon treatment with orthophosphoric acid in acetic acid underwent cyclisation and resulted in the formation of above titled compounds 5a-f. All synthesized compounds were characterized on the basis of its physical constant, analytical and spectral studies. Further these compounds were evaluated for their antibacterial and antifungal activities.