136513-92-3

Basic information

• Product Name: 2-{N'-[1-Phenyl-meth-(E)-ylidene]-hydrazino}-thiazole-4-carboxylic acid; hydrobromide
• Synonyms: 2-{N'-[1-Phenyl-meth-(E)-ylidene]-hydrazino}-thiazole-4-carboxylic acid; hydrobromide
• CAS NO: 136513-92-3
• Molecular Weight: 328.189
• Mol File: 136513-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{N'-[1-Phenyl-meth-(E)-ylidene]-hydrazino}-thiazole-4-carboxylic acid; hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{N'-[1-Phenyl-meth-(E)-ylidene]-hydrazino}-thiazole-4-carboxylic acid; hydrobromide(136513-92-3)
• EPA Substance Registry System: 2-{N'-[1-Phenyl-meth-(E)-ylidene]-hydrazino}-thiazole-4-carboxylic acid; hydrobromide(136513-92-3)

Safety Data

• Hazardous Substances Data: 136513-92-3(Hazardous Substances Data)

Upstream product

• 1113-59-3 bromopyruvic acid 
• 1627-73-2 1-benzylidene thiosemicarbazide 

Downstream Products

• 136265-66-2 benzaldehyde 4-carboxy-5-bromo-2-thiazolylhydrazone 
• 136265-55-9 2-benzylidenehydrazino-4-carboxythiazole 

Relevant articles and documents

SYNTHESIS AND SOME REACTIONS OF 4-CARBOXY-2-THIAZOLYLHYDRAZONES

The condensation of thiosemicarbazones with bromopyruvic acid gives thiazolylhydrazone hydrobromides, which were converted to the free bases.The question of the site of protonation was studied by PMR spectroscopy.The possibility of self-protonation in 4-carboxythiazolylhydrazone crystals is not excluded.The thiazolylhydrazones are brominated in the 5 position.Both cyclization to thiazolyltriazoles and the Chetteueya-Walker reaction are realized in the case of oxidation with lead tetraacetate.