13652-34-1Relevant academic research and scientific papers
Geometry-Retentive C-Alkenylation of Lithiated α-Aminonitriles: Quaternary α-Alkenyl Amino Acids and Hydantoins
Mas-Roselló, Josep,Hachisu, Shuji,Clayden, Jonathan
, p. 10750 - 10754 (2017)
α-Amino nitriles tethered to alkenes through a urea linkage undergo intramolecular C-alkenylation on treatment with base by attack of the lithionitrile derivatives on the N′-alkenyl group. A geometry-retentive alkene shift affords stereospecifically the E
