13653-23-1Relevant academic research and scientific papers
One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent
Kangani, Cyrous O.,Kelley, David E.
, p. 8917 - 8920 (2005)
A mild and highly efficient one pot-one step condensation and/or condensation-cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2,2-dimethyl-1-propanol resulted with excellent yields.
A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
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Paragraph 0078-0084; 0088-0089, (2016/12/01)
An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.
A continuous water removal product and production method
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Paragraph 0020; 0021; 0022; 0023, (2017/04/08)
The invention relates to a method for continuous water removal production of amide product; first, ammonium salt is produced by pre neutralization reaction of raw material carboxylic acid and amine, the ammonium salt is further dehydrated to obtain amide and by-product water. According to the method, by countercurrent contact recycle gas and raw material amine desorption, carrying, condensation separation, the by-product water is timely moved out of the reaction section, the reaction is promoted, the amine circulation proportion is reduced, and the material loss is reduced. The amide product prepared by the method not only can be used in natural organic carboxylic acids, and is also applicable to synthesized aromatic carboxylic acids, the process is clean and environmentally-friendly; and the product amide is high in purity and free of salt.
Multimeric Oleamide Derivative Having Connexin-26 Inhibiting Potency and Use Thereof in Cancer Therapy, etc.
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Page/Page column 6, (2010/11/30)
The present invention relates to multimeric oleamide derivatives having connexin 26 inhibitory activities and embraces the dimer oleamide derivatives represented by the following formula (1) or a pharmacologically acceptable salt thereof: where n denotes an integer of 3, 5, or 8. The novel oleamide derivatives of the present invention can be used not only as research reagents, but also in a wide industrial field because they exhibit useful bioactivities such as cancer metastasis/growth inhibition. Thus they have various applications, such as in medicines, supplements, and functional foods, in addition to cancer-preventive and cancer-therapeutic drugs.
A convenient method for the synthesis and one-pot reaction of acyl chlorides using a scavenging resin
Girard,Tranchant,Niore,Herscovici
, p. 1577 - 1580 (2007/10/03)
A simple, efficient and fast method for the preparation of acyl halides from fatty carboxylic acids using a solid phase scavenging approach is presented herein. The title compounds can then be isolated, used as a solution or react in one-pot to form esters and amides with good to excellent yields.
