1365349-84-3Relevant academic research and scientific papers
Ionic-liquid-catalyzed green synthesis of coumarin derivatives under solvent-free conditions
Shaterian, Hamid Reza,Aghakhanizadeh, Morteza
, p. 1690 - 1696 (2013)
Broensted acidic ionic liquids, namely 2-pyrrolidonium hydrogen sulfate, N-methyl-2-pyrrolidonium hydrogen sulfate, N-methyl-2-pyrrolidonium dihydrogen phosphate, (4-sulfobutyl)tris(4-sulfophenyl)phosphonium hydrogen sulfate, and triphenyl(propyl-3-sulfonyl)phosphonium toluenesulfonate, catalyzed efficient Pechmann condensation of phloroglucinol with β-keto ethyl/methyl esters. 5,7-Dihydroxy-4-methylcoumarin and 5,7-dihydroxy-4-phenylcoumarin were prepared in good to excellent yields under mild, ambient, and solvent-free conditions. Pyrano[2,3-h]coumarins were then prepared by one-pot three-component reactions of 5,7-dihydroxy-4-subsituted coumarin, malononitrile, and aldehydes in the presence of catalytic amounts of Broensted basic ionic liquids, namely 2-hydroxyethylammonium formate, 3-hydroxypropanaminium acetate, 1-butyl-3-methylimidazolium hydroxide, pyrrolidinium formate, and pyrrolidinium acetate, under thermal solvent-free conditions. The catalysts are environmentally benign and can be easily prepared, stored, and recovered without significant loss of activity.
Nano-Fe3O4@SiO2-supported boron sulfonic acid as a novel magnetically heterogeneous catalyst for the synthesis of pyrano coumarins
Farahi, Mahnaz,Karami, Bahador,Keshavarz, Raziyeh,Khosravian, Foroogh
, p. 46644 - 46650 (2017/10/13)
In this study, a novel magnetically heterogeneous catalyst based on the immobilization of boron sulfonic acid onto Fe3O4@SiO2 nanoparticles (Fe3O4@SiO2-BSA) is reported. Fe3Osub
Alternative two-step route to khellactone analogues using silica tungstic acid and sodium hydrogen phosphate
Karami, Bahador,Khodabakhshi, Saeed,Eskandari, Khalil
, p. 1474 - 1478 (2013/07/26)
A series of coumarins was synthesised via the silica tungstic acid-catalysed Pechmann reaction; some of these were employed for known three-component reactions with aromatic aldehydes and malononitrile in the presence of sodium hydrogen phosphate (Na2HPO4) as a basic catalyst, affording a variety of potentially anti-HIV active khellactone analogues.
A one-pot, three-component synthesis of new pyrano[2,3-h]coumarin derivatives
Karami, Bahador,Khodabakhshi, Saeed,Eskandari, Khalil
experimental part, p. 1445 - 1446 (2012/04/10)
The reaction between 5,7-dihydroxy-4-substituted coumarin, malononitrile, and aromatic aldehydes in the presence of a catalytic amount of K 2CO3 as a basic catalyst leads to new pyrano[2,3-h] coumarin derivatives in good to excellent
