1365392-52-4Relevant articles and documents
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase
Hieke, Martina,R?dl, Carmen B.,Wisniewska, Joanna M.,La Buscató, Estel.,Stark, Holger,Schubert-Zsilavecz, Manfred,Steinhilber, Dieter,Hofmann, Bettina,Proschak, Ewgenij
supporting information; experimental part, p. 1969 - 1975 (2012/04/17)
A novel class of 5-lipoxygenase (5-LO) inhibitors characterized by a central imidazo[1,2-a]pyridine scaffold, a cyclohexyl moiety and an aromatic system, is presented. This scaffold was identified in a virtual screening study and exhibits promising inhibi