1365658-64-5Relevant academic research and scientific papers
Consecutive cross-coupling reactions of 2,2-difluoro-1-iodoethenyl tosylate with boronic acids: Efficient synthesis of 1,1-diaryl-2,2-difluoroethenes
Kim, Ju Hee,Choi, Su Jeong,Jeong, In Howa
, p. 2470 - 2475 (2013)
The cross-coupling reactions of 2,2-difluoro-1-iodoethenyl tosylate (2) with 2 equiv of boronic acids in the presence of catalytic amounts of Pd(OAc)2 and Na2CO3 afforded the mono-coupled products 3 and 5 in high yields. The use of 4 equiv of boronic acid
Preparation of (2,2-difluoroethenylidene)bis(tributylstannane) and arylation reaction: Efficient approach to 1,1-diaryl-2,2-difluoroethenes
Han, Seung Yeon,Lee, Hyo Young,Jeon, Jong Hee,Jeong, In Howa
supporting information; experimental part, p. 1833 - 1836 (2012/05/04)
Reaction of 2,2-difluoro-1-tributylstannylethenyl p-toluenesulfonate (1) with bis(tributyltin) in the presence of 5 mol % Pd(PPh3)4 and 30 equiv LiBr in THF at reflux temperature for 7 h afforded (2,2-difluoroethenylidene)bis(tributylstannane) (2) in a 70% yield. Coupling reaction of 2 with aryl iodides in the presence of 5 mol % Pd(PPh 3)4 and 5 mol % CuI in DMF at 80 °C for 3-4 h provided the coupled products 3 in 59-85% yields.
