136579-82-3

Upstream product

• 135462-61-2 methyl 2-methoxy-4-methyl-5-phenyl-furan-3-carboxylate 
• 673-32-5 1-Phenylprop-1-yne 
• 135462-54-3 methyl 5-hydroperoxy-2,2-dimethoxy-4-methyl-5-phenyl-2,5-dihydrofuran-3-carboxylate 

Downstream Products

• 136579-84-5 5-Hydroxy-4-methyl-2-oxo-5-phenyl-2,5-dihydro-furan-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Photosensitized oxidation of furans; part 17: A simple method for the synthesis of 5-hydroperoxyfuran-2(5H)-ones

The 5-hydroperoxyfuran-2(5H)-ones 3 are synthesized by acid hydrolysis of the dihydrofurans 1 which are prepared in one-pot procedure by reaction of the corresponding furans 4 with singlet oxygen and methanol. The synthetic method has a wide range of applicability; however, compounds 3 unsubstituted at C-4 cannot be prepared since the corresponding dihydrofurans 1 are not formed.

A Further Selective Pathway in Thermal Conversion of 2,5-Epidioxy-2-alkoxy-2,5-dihydrofurans (2-Alkoxyfuran endo-Peroxides). Synthesis of the First 5-Hydroperoxyfuran-2(5H)-ones

Thermal conversion of the epidioxydihydrofurans 1 leads, via dioxyetanes 3, to the stereoisomeric dimers 4 which have a structural relationship with antitumor cyclic peroxides and represent convenient starting materials for several multifunctional compoun