136581-99-2Relevant academic research and scientific papers
Synthesis and antimicrobial activity of N-substituted-β-amino acid derivatives containing 2-hydroxyphenyl, benzo[b]phenoxazine and quinoxaline moieties
Mickeviien, Kristina,Kantminien, Kristina,Baranauskait, Rta,Stasevych, Maryna,Komarovska-Porokhnyavets, Olena,Novikov, Volodymyr
, p. 3170 - 3189 (2015/04/14)
3-[(2-Hydroxyphenyl)amino]butanoic and 3-[(2-hydroxy-5-methyl(chloro)phenyl)amino]butanoic acids were converted to a series of derivatives containing hydrazide, pyrrole and chloroquinoxaline moieties. The corresponding benzo[b]phenoxazine derivatives were synthesized by the reaction of the obtained compounds with 2,3-dichloro-1,4-naphthoquinone. Five of the synthesized compounds exhibited good antimicrobial activity against Staphylococcus aureus and Mycobacterium luteum, whereas three compounds showed significant antifungal activity against Candida tenuis and Aspergillus niger.
SYNTHESIS AND CYCLIZATION OF N-(2-HYDROXYPHENYL)- AND N-(2-BENZYLOXYPHENYL)-β-ALANINES
Mitskyavichyus, V. Yu.,Baltrushis, R. S.,Beresnevichyus, Z.-I. G.
, p. 420 - 423 (2007/10/02)
N-Substituted β-alanines have been synthesized by treating o-aminophenol or o-benzyloxyaniline with acrylic, methacrylic, or crotonic acids.Their cyclization to 2-benzoxazolinones and dihydro-2,4(1H,3H)-pyrimidinediones has been studied.
