136583-40-9

Basic information

• Product Name: Ethyl N--L-prolinate
• Synonyms: Ethyl N--L-prolinate
• CAS NO: 136583-40-9
• Molecular Weight: 474.6
• Mol File: 136583-40-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethyl N--L-prolinate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl N--L-prolinate(136583-40-9)
• EPA Substance Registry System: Ethyl N--L-prolinate(136583-40-9)

Safety Data

• Hazardous Substances Data: 136583-40-9(Hazardous Substances Data)

Upstream product

• 134038-43-0 (S)-1-((E)-2-Nitro-5-phenyl-pent-4-enoyl)-pyrrolidine-2-carboxylic acid ethyl ester 
• 129222-49-7 N-Nitroacetyl-(S)-proline ethyl ester 
• 21040-45-9 Cinnamyl acetate 
• 108-24-7 acetic anhydride 
• 136583-30-7 Ethyl N-(2-Nitro-2,2-bis(3-phenylprop-2-en-1-yl)acetyl)-L-prolinate 

Relevant articles and documents

Nitroacetyl Group as a Peptide Synthon: Synthesis of Dipeptides with an α,α-Bisallylglycine Residue at the N-Terminus

N-Nitroacetyl derivatives of L-proline, L-valine, and L-phenylalanine esters were prepared in two steps under mild conditions (Scheme 2).Regiospecific mono- and bis-allylation of these nitroacetyl derivatives were accomplished in presence of a Pd(0) catalyst.The bis-allyl derivatives 7-9 were obtained in 40-75 percent yield.The tertiary NO2 group in these compounds could be transformed into an acetylamino group by Zn/AcOH/Ac2O.The final products 11-13 are dipeptides in which the N-terminal glycine residue bears two α-allyl substituents.