1365839-67-3

Upstream product

• 1365839-65-1 C₂₇H₃₁NO₅S 
• 1365839-78-6 (±)-(2E)-ethylthio-2-ethylidene-5-hydroxy-3-(benzyloxymethyl)pentanoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 74611-95-3 S-ethyl 2-butene thioate 
• 74611-95-3 (E)-thiobut-2-ene-oic acid (S)-ethyl ester 
• 1365839-66-2 C₂₇H₃₁NO₅S 

Downstream Products

• 1365839-79-7 (±)-(2E)-3-(benzyloxymethyl)-2-ethylidene-5-(p-toluenesulfonyl)oxypentanal 
• 1365839-68-4 (±)-(2E)-3-(benzyloxymethyl)-2-ethylidene-5-(p-toluenesulfonyl)oxy-1-pentanol 
• 1365839-80-0 (±)-(2E)-6-azido-4-(benzyloxymethyl)-3-(hydroxymethyl)-2-hexene 
• 1365839-69-5 (±)-(2E)-6-azido-4-(benzyloxymethyl)-3-(pivaloyloxymethyl)-2-hexene 
• 1365839-70-8 C₂₇H₃₂N₄O₅S 
• 1365839-71-9 (±)-(3E)-2-(azidoethyl)-[1-(N-benzenesulfonylindole-2-yl)]-3-(pivaloyloxymethyl)-3-penten-1-one 

Relevant academic research and scientific papers

Structure determination and total synthesis of (+)-16-hydroxy-16,22- dihydroapparicine

Herein, we describe the first asymmetric total synthesis and determination of the relative and absolute stereochemistry of naturally occurring 16-hydroxy-16,22-dihydroapparicine. The key steps include 1) a novel phosphinimine-mediated cascade reaction to

The first total synthesis and reassignment of the relative stereochemistry of 16-hydroxy-16,22-dihydroapparicine

We report the first total synthesis and reassignment of the relative stereochemistry of naturally occurring 16-hydroxy-16,22-dihydroapparicine. Our novel route proceeds by a cascade reaction to efficiently construct a 1-azabicyclo[4.2.2]decane core, along