136587-00-3

Basic information

• Product Name: DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE
• Synonyms: DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE;NITROTRIESTER;DI-TERT-BUTYL-4-NITRO-4-(2-BOC ETHYL)HEPTANEDIOATE;DI-TERT-BUTYL 4-NITRO-4-(2-TERT-BUTOXYCARBONYLETHYL)HEPTANEDIOATE
• CAS NO: 136587-00-3
• Molecular Formula: C₂₂H₃₉NO₈
• Molecular Weight: 445.55
• Product Categories: Dendrimers;Dendron;Newkome Dendrimers
• Mol File: 136587-00-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 503.5°Cat760mmHg
• Flash Point: 156.4°C
• Appearance: /
• Density: 1.073g/cm³
• Vapor Pressure: 2.9E-10mmHg at 25°C
• Refractive Index: 1.467
• CAS DataBase Reference: DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE(136587-00-3)
• EPA Substance Registry System: DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE(136587-00-3)

Safety Data

• Hazardous Substances Data: 136587-00-3(Hazardous Substances Data)

Usage

General Description

DI-T-BUTYL 4-[2-(T-BUTOXYCARBONYL)ETHYL]-4-NITROHEPTANEDICARBOXYLATE, also known as TBNE, is a chemical compound that belongs to the category of di-tert-butyl esters. It is used in the synthesis of complex molecules and in the production of pharmaceuticals, agrochemicals, and materials. TBNE has several applications in the field of organic chemistry, such as in the protection of functional groups and in the preparation of various building blocks for organic synthesis. It is a versatile and important chemical compound with a wide range of uses in the industry.

InChI:InChI=1/C22H39NO8/c1-19(2,3)29-16(24)10-13-22(23(27)28,14-11-17(25)30-20(4,5)6)15-12-18(26)31-21(7,8)9/h10-15H2,1-9H3

Upstream product

• 75-52-5 nitromethane 
• 1663-39-4 tert-Butyl acrylate 

Downstream Products

• 798576-99-5 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(2-carboxyethyl)heptanedioic acid 
• 1217553-84-8 4-(2-tert-butoxycarbonyl-ethyl)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-heptanedioic acid di-tert-butyl ester 
• 1326757-15-6 C₃₄H₄₂N₄O₁₁ 
• 926649-26-5 N-[tris(2-dodecylaminocarbonyl-ethyl)methyl]-N'-[tris(2-tert-butoxycarbonyl-ethyl)methyl]terephthaldiamide 
• 59085-15-3 4-(2-carboxyethyl)-4-nitroheptanedioic acid 
• 136586-99-7 4-amino-4-(2-tert-butoxycarbonylethyl)heptanedioic acid di-tertbutyl ester 

Relevant articles and documents

Multifunctional degradable nanoparticles with control over size and functionalities

In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymers and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

SUGAR-LINKER-DRUG CONJUGATES

The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using thern are also provided.

CONJUGATES AND THEIR USES IN MOLECULAR IMAGING

The present invention relates to bifunctional compounds, the bifunctional compounds for use in molecular imaging and therapy, methods of molecular imaging using the bifunctional compounds and kits including the bifunctional compounds for use molecular imaging. The bifunctional compounds have a tripodal hydroxypyridinone chelating portion and may be conjugated to a targeting group so that the compounds target specific cells or tissues in a subject.