136598-92-0

Basic information

• Product Name: bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide
• Synonyms: bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide
• CAS NO: 136598-92-0
• Molecular Weight: 568.619
• Mol File: 136598-92-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide(CAS DataBase Reference)
• NIST Chemistry Reference: bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide(136598-92-0)
• EPA Substance Registry System: bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide(136598-92-0)

Safety Data

• Hazardous Substances Data: 136598-92-0(Hazardous Substances Data)

Upstream product

• 135272-34-3 (2R,3R)-2-(2,4-difluorophenyl)-3-mercapto-1-[1H-1,2,4-triazol-1-yl]-2-butanol 

Downstream Products

• 145942-55-8 N-benzyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-02-5 N-cyclohexyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfenamide 
• 145942-06-9 N-cyclopropyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfenamide 
• 145942-74-1 N-methyl-N-(2-pyrimidinyl)-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-10-5 N-ethyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2butane]sulfenamide 
• 145942-98-9 N-butyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfenamide 
• 145942-58-1 N-dodecyl-N-methyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-64-9 N-(2-fluoro-4-trifluoromethylbenzyl)-N-methyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-63-8 N-methyl-N-(4-trifluoromethylbenzyl)-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-57-0 N-(3,4-dimethoxybenzyl)-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-56-9 N-diphenylmethyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 145942-09-2 N-methyl-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4(1H-1,2,4-triazol-1-yl)-2-butane]sulfonamide 
• 1026454-19-2 (2R,3R)-2-(2,4-Difluoro-phenyl)-1-[1,2,4]triazol-1-yl-3-[4-(4-trifluoromethyl-phenyl)-piperazin-1-ylsulfanyl]-butan-2-ol 

Relevant articles and documents

Optically active antifungal azoles. II. Synthesis and antifungal activity of polysulfide derivatives of (2R,3R)-2-(2,4-difluorophenyl)-3-mercapto-1- (1H-1,2,4-triazol-1-yl)-2-butanol

In an effort to find potent antifungal agents, a variety of optically active triazole derivatives with a polysulfide structure, 3, 4 and 5, were prepared and evaluated for antifungal activity against Candida albicans in vitro and in vivo. The symmetrical