Optically active antifungal azoles. II. Synthesis and antifungal activity of polysulfide derivatives of (2R,3R)-2-(2,4-difluorophenyl)-3-mercapto-1- (1H-1,2,4-triazol-1-yl)-2-butanol

DOI: 10.1248/cpb.41.1043

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1043 - 1048 (1993)

Update date:2022-08-04

Topics:

Authors:

Tasaka Tasaka

Tamura Tamura

Matsushita

Hayashi Hayashi

Okonogi Okonogi

Itoh Itoh

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.41.1043

In an effort to find potent antifungal agents, a variety of optically active triazole derivatives with a polysulfide structure, 3, 4 and 5, were prepared and evaluated for antifungal activity against Candida albicans in vitro and in vivo. The symmetrical

Full text of DOI:10.1248/cpb.41.1043

NII-Electronic Library Service

Products guided by the article

Product name:bis<(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl> disulfide

Cas No:136598-92-0

R&D Labs maybe for 136598-92-0

shanghai meicheng chemical co .,ltd(expird)

Contact:+86-21-50677091

Address:Room 302, Building 7, No.1000, Jinhai Road
Shaanxi Lighte Optoelectronics Material Co., Ltd.

Contact:+86-29-88320728-622/619/620

Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.

Contact:--

Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
Huayang chemical Co., LTD

Contact:+86-18653358619

Address:zibo
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China

Relevant to this article

Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol

Doi:10.1016/j.bmc.2012.01.047
(2012)
Kinetically Controlled Stereoselective Access to Branched 1,3-Dienes by Ru-Catalyzed Remote Conjugative Isomerization

Doi:10.1021/acscatal.1c02144
(2021)
Cobalt(II)acetate promoted oxidative addition of 1,3-dicarbonyl compounds to alkenes under aerobic conditions

Doi:10.1016/S0040-4020(01)86573-X
(1991)
Nickel-catalyzed cross-couplings of organosilicon reagents with unactivated secondary alkyl bromides

Doi:10.1021/ja047433c
(2004)
Stereospecific synthesis of branched-chain sugars by a novel aldol-type cyclocondensation

Doi:10.1016/0008-6215(92)84176-S
(1991)
Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction

Doi:10.1016/j.tetasy.2012.01.021
(2012)

Article Doi