1366000-20-5Relevant articles and documents
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: A promising approach for treating pain and inflammation
Baraldi, Pier Giovanni,Romagnoli, Romeo,Saponaro, Giulia,Aghazadeh Tabrizi, Mojgan,Baraldi, Stefania,Pedretti, Pamela,Fusi, Camilla,Nassini, Romina,Materazzi, Serena,Geppetti, Pierangelo,Preti, Delia
, p. 1690 - 1698 (2012/04/23)
The transient receptor potential ankyrin 1 (TRPA1) channel is activated by a series of by-products of oxidative/nitrative stress, produced under inflammatory conditions or in the case of tissue damage, thus generating inflammatory and neuropathic pain and