136603-56-0Relevant academic research and scientific papers
Design and synthesis of 3-trifluoromethyl-3h-pyrazoles and further investigations of their transformation to 1h-pyrazoles
Sha, Qiang,Liu, Haixuan,Wei, Yunyang
, p. 7707 - 7715 (2015/04/22)
An efficient intramolecular cycloaddition strategy for the synthesis of trifluoromethyl-substituted 3H-pyrazoles was developed. Subsequently, their wide applications were demonstrated: they (1) react with dioxane by a radical process and (2) undergo [1,5] sigmatropic rearrangements. These applications are useful as the products were obtained in high yields and with excellent regioselectivity.
TRIFLUOROMETHYL-p-TOLYLDIAZOMETHANE IN 1,3-DIPOLAR CYCLOADDITION REACTIONS
Linev, V. V.,Kolomiets, A. F.,Fokin, A. V.
, p. 1406 - 1409 (2007/10/02)
Trifluoromethyl-p-tolyldiazomethane (I) forms -cycloadducts with activated alkenes and alkynes.The products of these regiospecific reactions are substituted pyrazolines (II)-(VI) and pyrazoles (VIII)-(X).Reaction of (I) with fumarates, trifluoropyr
