136617-41-9Relevant academic research and scientific papers
Conversion of (-)-α-Narcotine into (+)-Papaveroxinoline and (+)-Macrantaline
Rozwadowska, Maria D.,Banaszynski, Slawomir
, p. 1357 - 1360 (2007/10/02)
(-)-α-Narcotine (5), a phthalideisoquinoline alkaloid, is converted into two secoberbines: (+)-papaveroxinoline (3) and (+)-macrantaline (1).The reaction sequence involves reduction of 5 to the diol 6 followed by selective monoacetylation to (+)-3.Hydrogenolysis of the latter affords (+)-1.Key Words: Phthalideisoquinoline alkaloids / Narcotine / Secoberbines / Macrantaline / Papveroxinoline
