13662-46-9Relevant academic research and scientific papers
Silylative aromatization of: P -quinone methides under metal and solvent free conditions
Li, Tingting,Wu, Yuzhu,Duan, Wenzeng,Ma, Yudao
, p. 17860 - 17864 (2021)
A base-mediated silylation reaction leading to benzyl silanes has been developed. Under transition-metal and solvent free conditions, the silylation of a wide array of p-quinone methides is achieved using a Cs2CO3 catalyst in yields up to 96%. Carboxylati
Synthesis of Malononitrile-Substituted Diarylmethines via 1,6-Addition of Masked Acyl Cyanides to para -Quinone Methides
Zhao, Kun,Zhi, Ying,Wang, Ai,Enders, Dieter
, p. 872 - 880 (2017/11/29)
An efficient method for the synthesis of malononitrile-substituted diarylmethines through 1,6-conjugate addition of para -quinone methides with masked acyl cyanide (MAC) reagents has been developed. Under mild conditions, the scalable reaction occurs in good to excellent yields providing a straightforward access to a series of malononitrile-substituted diarylmethines. The synthetic utility of this protocol has been demonstrated in the synthesis of bioactive compounds.
