13662-55-0Relevant academic research and scientific papers
SAR studies of differently functionalized 4′-phenylchalcone based compounds as inhibitors of cathepsins B, H and L
Ravish, Indu,Raghav, Neera
, p. 50440 - 50453 (2015/06/25)
Conditions related to the elevated levels of cathepsin B [3.4.22.1], cathepsin H [3.4.22.16] and cathepsin L [3.4.22.15] in various cancerous, rheumatoid arthritis and tissue degenerative disorders motivate the design, synthesis and evaluation of compound
Synthesis and antibacterial activity of some 5-(4-biphenylyl)-7-aryl[3,4-d] [1,2,3]-benzothiadiazoles
Balasankar,Gopalakrishnan,Nagarajan
, p. 728 - 731 (2007/10/03)
A series of 5-(4-biphenylyl)-7-aryl[3,4-d] [1,2,3]-benzothiadiazoles were synthesized, characterized by IR, NMR and elemental analysis and evaluated for in vitro antibacterial activity against some Gram-positive and Gram-negative bacteria. The antibacterial data revealed that compounds 7a-j had better activity against tested Gram-positive organisms than the reference ciprofloxacin and norfloxacin. However, the compounds were nearly inactive against Gram-negative bacteria. Compound 7c and 7d were the most active compounds against Gram-positive bacteria.
Synthesis and antibacterial activities of some 2-amino-4,6- diarylpyrimidines
Balasankar,Nagarajan
, p. 451 - 456 (2007/10/03)
A series of 2-aminopyrimidines have been prepared by the condensation of 1-(1,1′-biphenyl-4-yl)-3-arylprop-2-en-1-ones with guanidine-nitrate and characterized on the basis of analytical and spectral data. The compounds have been screened for their antibacterial activities.
