13663-04-2Relevant academic research and scientific papers
An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions
Lu, Hong-Fei,Zhou, Jun-Tao,Cheng, He-Long,Sun, Lei-Lei,Yang, Fei-Fei,Wu, Run-Ze,Gao, Yu-Hua,Luo, Zhi-Bin
, p. 11174 - 11184 (2014/01/06)
An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)2[BiCl6] Cl·H2O (1 mol %). This catalyst can be reused several times without significant loss of activity.
Efficient synthesis of-Hydroxy sulfides and-Hydroxy sulfoxides catalyzed by Cu/MgO under solvent-free conditions
Das, Biswanath,Balasubramanyam, Penagaluri,Krishnaiah, Maddeboina,Veeranjaneyulu, Boyapati,Sudhakar, Dega
experimental part, p. 2113 - 2121 (2010/08/13)
Regio-, stereo-, and chemoselective ring opening of epoxides with thiols using Cu/MgO as a heterogeneous catalyst has efficiently been carried out to produce the corresponding β-hydroxy sulfides in excellent yields at room temperature under solvent-free c
Regioselective reaction of epoxides with disulfides using Zn/AlCl 3 system: A simple synthesis of β-hydroxy sulfides
Movassagh,Sobhani,Kheirdoush,Fadaei
, p. 3103 - 3108 (2007/10/03)
Epoxides are regioselectively cleaved by zinc thiolate intermediate, generated from disulfides in the presence of Zn/AlCl3 system, to afford high yields of the corresponding β-hydroxy sulfides.
Kinetic resolution of β- and γ-hydroxy sulfides by fungal lipase from Humicola lanuginosa
Singh, Satwinder,Kumar, Subodh,Chimni, Swapandeep Singh
, p. 231 - 240 (2007/10/03)
Racemic β- and γ-hydroxy sulfides were resolved by Humicola lanuginosa lipase catalyzed transesterification using vinyl acetate both as acyl donor and solvent. The effect of substituents and spacer length on rate of reaction and enantioselectivity is obse
2-(Arylthio)ethanamines and &α-(Arylthio)propionamides with Antidepressant Activity
Nair, M. D.,David, J.,Nagarajan, K.
, p. 940 - 947 (2007/10/02)
Reaction of aziridine with thiophenols affords 2-arylthioethanamines; with 2-methylaziridine, ring opening occurs regiospecifically to provide 1-arylthio-2-propanamines.The structure of one member of this group, 1-(4-chlorophenylthio)-2-propanamine (7), has been proved by other unambiguous syntheses. 7 and isomer 12 arise from the alkylation of 4-chlorothiophenol with 2-chloropropylamine as well as from the displacement of the tosyl group in 1-(4-chlorophenylthio)-2-tosyloxypropane (13).Alkylation of 4-chlorothiophenol with α-chloropropionamide affords 11 which leads to 12 on LAH reduction.Ethanamines and propanamines are converted into guanidines, amides, ureas and thioureas.Many arylthioethanamines, e.g. 7, 22, 28, 38 and 39 (as HCl salts) and α-arylthiopropionamides, e.g. 11, 86, 91, 93 and 96 exhibit good activity in the DOPA potentiation and reserpine antagonism tests.Among these, 7 HCl is the most potent and does not inhibit rat brain MAO activity.In clinical trials, C 2998-Go compares favourably with imipramine.
