25784-83-2

Basic information

• Product Name: (4-CHLOROPHENYLTHIO)ACETONE
• Synonyms: 1-[(4-CHLOROPHENYL)THIO]-2-PROPANONE;1-(4-CHLOROPHENYLTHIO)PROPAN-2-ONE;(4-CHLOROPHENYLTHIO)ACETONE;(4-CHLOROPHENYLTHIO)PROPAN-2-ONE;LABOTEST-BB LT00455258;(4-Chlorophenylthio)-2-propanone;4-Chlorothiophenoxyacetone;(4-CHLOROPHENYLTHIO)PROPAN-2-ONE 97%
• CAS NO: 25784-83-2
• Molecular Formula: C₉H₉ClOS
• Molecular Weight: 200.69
• Mol File: 25784-83-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 38-42 °C(lit.)
• Boiling Point: 287.4 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: White to yellow powder, crystals or crystalline powder and/or chunks
• Density: 1.24 g/cm³
• Vapor Pressure: 0.00249mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: (4-CHLOROPHENYLTHIO)ACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLOROPHENYLTHIO)ACETONE(25784-83-2)
• EPA Substance Registry System: (4-CHLOROPHENYLTHIO)ACETONE(25784-83-2)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 25784-83-2(Hazardous Substances Data)

Usage

General Description

(4-Chlorophenylthio)acetone, also known as 4-CPA, is a chemical compound characterized by the presence of chlorine and sulfur atoms. It's commonly used in the synthesis of other complex chemical compounds, particularly in pharmaceutical manufacturing. The chemical is also used in research and development processes. As a chemical, safety measures should be considered during its use due to potency and reactivity with other elements and compounds. The potential risks and hazards associated with the use of this chemical are generally well-documented and can be treated with appropriate chemicals handling procedures.

InChI:InChI=1/C9H9ClOS/c1-7(11)6-12-9-4-2-8(10)3-5-9/h2-5H,6H2,1H3

Upstream product

• 78-95-5 chloroacetone 
• 18803-44-6 sodium p-chlorothiophenolate 
• 108-22-5 Isopropenyl acetate 
• 106-54-7 p-Chlorothiophenol 
• 2564-83-2 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical 
• 106-46-7 para-dichlorobenzene 
• 123-54-6 acetylacetone 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 598-31-2 1-bromoacetone 
• 67-64-1 acetone 
• 869661-08-5 3-(4-chlorophenylsulfanylmethyl)-3-methyl-1,2,5-trioxaspiro[5.5]undecane 

Downstream Products

• 14803-75-9 2-<(4-chlorophenyl)thio>-4-nitrophenol 
• 336186-33-5 3-[(4-chlorophenyl)thio]-2,5-dimethyl-1H-indole 
• 107244-75-7 4-Amino-2-(4-chloro-phenylsulfanyl)-6-diethylaminomethyl-phenol; hydrochloride 
• 107244-92-8 4-(7-Chloro-1-oxy-quinolin-4-ylamino)-2-(4-chloro-phenylsulfanyl)-6-diethylaminomethyl-phenol 
• 107244-84-8 2-(4-Chloro-phenylsulfanyl)-4-(7-chloro-quinolin-4-ylamino)-6-diethylaminomethyl-phenol 
• 107244-67-7 N-[3-(4-Chloro-phenylsulfanyl)-5-diethylaminomethyl-4-hydroxy-phenyl]-acetamide 
• 107244-59-7 N-[3-(4-Chloro-phenylsulfanyl)-4-hydroxy-phenyl]-acetamide 
• 1198-51-2 3-(bromomethyl)-5-chloro-1-benzothiophene 
• 332887-44-2 1-(4-chlorophenylsulfinyl)nonan-2-one 
• 332887-45-3 1-(4-chlorophenylsulfinyl)hex-5-en-2-one 
• 170806-12-9 6,7-dichloro-2-methyl-3-(4-chlorophenyl)thioquinoxaline 1,4-dioxide 
• 112988-43-9 3-(4-Chloro-phenylsulfanyl)-2-hydroxy-2-methyl-propionitrile 
• 104864-60-0 N-[2-(4-Chloro-phenylsulfanyl)-1-methyl-ethyl]-formamide 
• 13663-04-2 (RS)-1-(p-chlorophenyl)thiopropan-2-ol 

Relevant articles and documents

Direct Synthesis of α-Sulfenylated Ketones under Electrochemical Conditions

We investigated the electrochemical sulfenylation reaction in both batch and continuous flow regimes, involving thiophenols/thiols and enol-acetates to yield α-sulfenylated ketones, without using additional oxidants or catalysts. Studies with different electrolytes were also performed, revealing that quaternary ammonium salts are the best mediators for this reaction. Notably, during the study of the reaction scope, a Boc-cysteine proved to be extremely tolerant to our protocol, thus increasing its relevance. The methodology also proved to be scalable in both batch and continuous flow conditions, opening up possibilities for further studies since these relevant functional groups are important moieties in organic synthesis.

Synthesis of α-arylthioacetones using TEMPO as the: C 3 synthon via a reaction cascade of sequential oxidation, skeletal rearrangement and C-S bond formation

Here, we present an unprecedented pathway to α-sulfenylated carbonyl compounds from commercially available thiols and universally employed TEMPO and its analogues, which act as C3 synthons through skeletal rearrangement under simple and metal-f

A sulfur-containing amino acid amide carbamate derivative and application thereof

The invention belongs to the field of plant fungicides, and relates to sulfur-containing amino acid amide carbamate derivatives of which the general formulas I are shown in the description and pharmaceutically acceptable salts of the sulfur-containing amino acid amide carbamate derivatives. In the general formulas I, substituent groups R1, R2 and n are defined in the description. The invention further relates to preparation methods of compounds related to the general formulas I, special intermediates developed for the preparation of the compounds, and application of the compounds to prevention and control of plant diseases.