1366425-32-2

Basic information

• Product Name: 7-oxo-7-phenylhept-5-ynenitrile
• Synonyms: 7-oxo-7-phenylhept-5-ynenitrile
• CAS NO: 1366425-32-2
• Molecular Weight: 197.236
• Mol File: 1366425-32-2.mol

Chemical Properties

• CAS DataBase Reference: 7-oxo-7-phenylhept-5-ynenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 7-oxo-7-phenylhept-5-ynenitrile(1366425-32-2)
• EPA Substance Registry System: 7-oxo-7-phenylhept-5-ynenitrile(1366425-32-2)

Safety Data

• Hazardous Substances Data: 1366425-32-2(Hazardous Substances Data)

Upstream product

• 14918-21-9 5-hexynonitrile 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Photoinduced Synthesis of P-Perfluoroalkylated Phosphines from Triarylphosphines and Their Application in the Copper-Free Cross-Coupling of Acid Chlorides and Terminal Alkynes

A practical synthesis yielding P-perfluoroalkylated phosphines from triarylphosphines and perfluoroalkyl iodides has been developed. The photoinduced reaction involves the substitution of aryl groups on the phosphorus atom with perfluoroalkyl groups to successfully afford P-perfluoroalkylated phosphines. In addition, the P-perfluoroalkylated phosphines were found to promote the Cu-free cross-coupling reaction of acid chlorides with terminal alkynes.

PHOSPHINE COMPOUND HAVING PERFLUORO GROUP, AND COMPLEX BETWEEN METAL AND PHOSPHINE HAVING PERFLUORO GROUP

PROBLEM TO BE SOLVED: To provide a perfluoroalkylphosphine compound, and a complex between a metal and the perfluoroalkylphosphine. SOLUTION: A perfluoroalkylphosphine compound is a phosphine compound represented by the general formula Rf-PR1R2. In the formula, R1 and R2 are each independently a substituted or unsubstituted hydrocarbon group; Rf is a perfluorinated hydrocarbon group. Also provided is a complex between the perfluoroalkylphosphine and a phosphine coordination metal. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

METHODS OF PRODUCING PHOSPHINE COMPOUND HAVING PERFLUORO GROUP AND COMPLEX BETWEEN METAL AND PHOSPHINE HAVING PERFLUORO GROUP

PROBLEM TO BE SOLVED: To provide methods of producing a perfluoroalkylphosphine compound improved in a phosphorus element yield and a chemical yield. SOLUTION: A method of producing a perfluoroalkylphosphine compound comprises either reacting a perfluoroalkyl iodide with, e.g., 2,4,6-trimethylbenzoyldiphenylphosphine oxide (TMDPO) or a triarylphosphine such as triphenylphosphine, which are easily available, in the presence of a radical generator such as azobis(isobutyronitrile) or light irradiation, or reacting TMDPO or the like with perfluoroalkyl iodide in the presence of diphenylphosphine, diethylphosphine, dicyclohexylphosphine or the like. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Pd-catalyzed coupling reaction of acid chlorides with terminal alkynes using 1-(2-pyridylethynyl)-2-(2-thienylethynyl)benzene ligand

In the presence of 1-(2-pyridylethynyl)-2-(2-thienylethynyl)benzene as a ligand, the direct synthesis of alkynones has accomplished by a Pd-catalyzed coupling reaction of acid chlorides with terminal acetylenes under mild conditions.