1366469-85-3Relevant academic research and scientific papers
Anionic Diels-Alder Chemistry of Cyclic Sodium Dien-1-olates Delivering Highly Stereoselective and Functionalized Polycyclic Adducts
Huang, Jing-Kai,Shia, Kak-Shan
, p. 5709 - 5713 (2021)
Anionic Diels-Alder chemistry of electron-deficient cross-conjugated vinylogous alkenones, providing highly stable sodium dienolate ion pairs as electron-rich dienes in the presence of a weak sodium base in THF, has been newly developed, leading to a single Diels-Alder adduct, in racemic form, in moderate to high yields (up to 97%, 37 examples).
Syntheses of structurally-simplified and fluorescently-labeled neovibsanin derivatives and analysis of their neurite outgrowth activity in PC12 cells
Imagawa, Hiroshi,Saijo, Hayato,Yamaguchi, Hitomi,Maekawa, Ken,Kurisaki, Takahiro,Yamamoto, Hirofumi,Nishizawa, Mugio,Oda, Masataka,Kabura, Michiko,Nagahama, Masahiro,Sakurai, Jun,Kubo, Miwa,Nakai, Megumi,Makino, Kosho,Ogata, Mitsuko,Takahashi, Hironobu,Fukuyama, Yoshiyasu
, p. 2089 - 2093 (2012/04/17)
The syntheses of several neovibsanin derivatives were carried out in order to elucidate the simple structure required for displaying neurite outgrowth activity. In addition, a fluorescent probe molecule was synthesized and the analysis of its behavior in the PC12 cell line showed that the neovibsanins accumulate on the outer edge of the cell at the site of formation of prominences.
