1366542-29-1Relevant articles and documents
Chelation controlled reductive amination of cyclic ketones to trans-4-methoxycyclohexylamines: 9-BBN reduction mediated with FeCl3
Qu, Bo,Haddad, Nizar,Rodriguez, Sonia,Lee, Heewon,Ma, Shengli,Zeng, Xingzhong,Reeves, Diana C.,Sidhu, Kanwar P.S.,Lorenz, Jon C.,Grinberg, Nelu,Busacca, Carl A.,Krishnamurthy, Dhileepkumar,Senanayake, Chris H.
experimental part, p. 1982 - 1986 (2012/05/05)
A novel trans-diastereoselective reductive amination of 4-substituted cyclohexanones is described using 9-BBN as reducing agent in the presence of FeCl3. The method permits efficient synthesis of structurally diverse 4-trans-alkoxycyclohexylami