136705-64-1

Basic information

• Product Name: (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE
• Synonyms: (2R,2'R,5R,5'R)-2,2'-5,5'-TETRAETHYL-1,1'-(O-PHENYLENE)DIPHOSPHOLANE;(-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE;(R,R)-ETHYL-DUPHOS;(R,R)-ET-DUPHOS;(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene, Kanata purity;(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene(r,r)-et-duphos;(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene,98+%(R,R)-Et-DUPHOS;(R,R)-Ethyl-DUPHOS, (2R,2μR,5R,5μR)-2,2μ-5,5μ-Tetraethyl-1,1μ-(o-phenylene)diphospholane
• CAS NO: 136705-64-1
• Molecular Formula: C₂₂H₃₆P₂
• Molecular Weight: 362.47
• Product Categories: organophosphine ligand
• Mol File: 136705-64-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: bp0.045 138-145°
• Flash Point: >230 °F
• Appearance: /
• Density: 1.01 g/mL at 25 °C
• Vapor Pressure: 1.67E-08mmHg at 25°C
• Refractive Index: n 20/D 1.6
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• Merck: 13,3499
• BRN: 4814174
• CAS DataBase Reference: (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(136705-64-1)
• EPA Substance Registry System: (-)-1,2-BIS((2R,5R)-2,5-DIETHYLPHOSPHOLANO)BENZENE(136705-64-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 1-10
• Hazardous Substances Data: 136705-64-1(Hazardous Substances Data)

Usage

Reactions

Ligand used in rhodium catalyzed asymmetric hydrogenation of 2-methylenesuccinamic acid. Cobalt-catalyzed asymmetric hydrogenation.

Uses

Different sources of media describe the Uses of 136705-64-1 differently. You can refer to the following data:
1. Catalyst for asymmetric hydrogenations.
2. DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

InChI:InChI=1/C22H36P2/c1-5-17-13-14-18(6-2)23(17)21-11-9-10-12-22(21)24-19(7-3)15-16-20(24)8-4/h9-12,17-20H,5-8,13-16H2,1-4H3/t17-,18-,19-,20-/m1/s1

Upstream product

• 136705-66-3 (3S,6S)-octane-3,6-diol 
• 80510-04-9 1,2-bis(phosphino)benzene 
• 136705-67-4 (S,S)-octane-3,6-diol cyclic sulfate 

Relevant articles and documents

Preparation and use of C2-symmetric bis(phospholanes): Production of α-amino acid derivatives via highly enantioselective hydrogenation reactions

A new class of chiral C2-symmetric bis(phospholane) ligands has been prepared and used in rhodium-catalyzed asymmetric hydrogenation reactions. We describe a practical, one-pot procedure which utilizes enantiomerically pure 1,4-diol cyclic sulf