136718-81-5Relevant articles and documents
Preparation of novel derivatives of pyridothiazine-1,1-dioxide and their CNS and antioxidant properties.
Malinka,Kaczmarz,Filipek,Sapa,Glod
, p. 737 - 746 (2007/10/03)
Starting from isothiazolopyridine-1,1-dioxide (1), corresponding derivatives of 3-aryl-4-hydroxypyrido[3,2-e]-1,2-thiazine-1,1-dioxide (6) possessing the 3-[4-(substituted-phenyl)piperazinyl]propyl or 3-(4-substituted-piperidinyl)propyl side chain by the
CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF
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Referential example 40, (2010/01/31)
A compound of the formula: wherein R1 is a hydrocarbon group, R2 is a hydrocarbon group having 2 or more carbon atoms, where R1 and R2 may in combination form, together with an adjacent nitrogen atom, a ring optionally having a substituent or substituents, R3 is a hydrocarbon group optionally having a substituent or substituents or a heterocyclic group optionally having a substituent or substituents, R4 is a hydrogen atom, a hydrocarbon group, a heterocyclic group and the like, E is a divalent chain hydrocarbon group and the like, G is CO or SO2, J is a nitrogen atom, a methine group and the like, and Q and R are each a divalent chain C1-3 hydrocarbon group and the like, and a salt thereof show a superior CCR5 antagonistic activity and are useful as agents for the prophylaxis or treatment of HIV infection of human peripheral blood mononuclear cells, particularly AIDS.
Parallel synthesis of a series of subtype-selective NMDA receptor antagonists
Gregory, Tracy F.,Wright, Jon L.,Wise, Lawrence D.,Meltzer, Leonard T.,Serpa, Kevin A.,Konkoy, Christopher S.,Whittemore, Edward R.,Woodward, Richard M.
, p. 527 - 529 (2007/10/03)
A series of 1-(heteroarylthioalkyl)-4-benzylpiperidines was rapidly synthesized through the use of parallel synthesis to investigate the binding affinity for the NR1A/2B receptor subtype. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.
