1367356-52-2Relevant academic research and scientific papers
Synthesis of new organophosphorus compounds using the atherton-todd reaction as a versatile tool
Wagner, Sebastian,Rakotomalala, Muriel,Bykov, Yana,Walter, Olaf,Doering, Manfred
experimental part, p. 216 - 222 (2012/07/13)
This article discusses the behavior of seven organophosphorus compounds under Atherton-Todd conditions. Therefore, the reactivity and selectivity of different (phen)oxaphosphinines, dioxaphosphinines, dioxaphosphinanes, and diphenylphosphine oxide with three nucleophiles were systematically studied. The results prove the versatility of the Atherton-Todd reaction to a broad range of organophosphorus compounds with different phosphorus environments and reactive Pi-H bonds. The nucleophiles studied in this article were chosen as model substrates for amines and alcohols. Because organophosphorus molecules are important and versatile compounds, for a broad field of applications, novel synthetic approaches are of interest to both academia and industry. As an example, the single-step synthesis of the bridged 1,3-phenylene bis(diphenylphosphinate) with potential flame-retardant properties was added to this study. In addition, the reaction is utilized for the synthesis of a novel organophosphorus anhydride.
