1367487-64-6Relevant academic research and scientific papers
Squaramide-catalysed enantionselective Mannich reaction of imines bearing a heterocycle with malonates
He, Hai-Xiao,Du, Da-Ming
, p. 16349 - 16358 (2013/09/23)
An efficient enantioselective Mannich reaction of imines bearing a heterocycle with malonates catalysed by a cinchona-based squaramide organocatalyst has been developed. This catalytic asymmetric reaction afforded the β-amino ester derivatives containing
Chiral cinchona alkaloid-derived thiourea catalyst for enantioselective synthesis of novel β-amino esters by Mannich reaction
Li, Weihua,Song, Baoan,Bhadury, Pinaki S.,Li, Liang,Wang, Zhenchao,Zhang, Xiaoyan,Hu, Deyu,Chen, Zhuo,Zhang, Yuping,Bai, Song,Wu, Jian,Yang, Song
experimental part, p. 223 - 231 (2012/06/01)
A cinchona alkaloid-derived thiourea catalyst has been designed to access new asymmetric β-amino esters bearing benzothiazole moiety by utilizing a Mannich reaction between an imine and a malonate. A simultaneous activation of the two imine functionalitie
Enantioselective synthesis of β-amino esters bearing a benzothiazole moiety via a Mannich-type reaction catalyzed by a cinchona alkaloid derivative
Li, Liang,Song, Bao-An,Bhadury, Pinaki S.,Zhang, Yu-Ping,Hu, De-Yu,Yang, Song
, p. 4743 - 4746 (2011/10/09)
Novel β-amino esters bearing a bioactive benzothiazole moiety were obtained with high enantioselectivities (up to 95 % ee) through a Mannich-type reaction of different imines with malonate in the presence of a new chiral cinchona alkaloid thiourea catalys
