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1-(2,3-dichloro-4-methoxyphenyl)ethanamine, also known as 2,3-Dichloro-4-methoxyamphetamine (DOI), is a chemical compound belonging to the phenylalkylamine derivatives class. It is a potent and selective serotonin 5-HT2A receptor agonist, characterized by its hallucinogenic properties and psychoactive effects on perception, thought, and mood. 1-(2,3-dichloro-4-methoxyphenyl)ethanamine has been a subject of research for its potential therapeutic applications in mental health disorders and for understanding its impact on brain and behavior. However, it is also classified as a controlled substance due to its potential for misuse and abuse.

1368225-72-2

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1368225-72-2 Usage

Uses

Used in Pharmaceutical Research:
1-(2,3-dichloro-4-methoxyphenyl)ethanamine is used as a research compound for investigating its potential therapeutic applications in treating various mental health disorders. Its agonistic action on the serotonin 5-HT2A receptor makes it a valuable tool for studying the receptor's role in psychiatric conditions and for developing new treatment strategies.
Used in Neuroscience Research:
In neuroscience, 1-(2,3-dichloro-4-methoxyphenyl)ethanamine is used as a research tool to understand the effects of psychoactive substances on brain function and behavior. Its ability to cause changes in perception, thought, and mood provides insights into the underlying mechanisms of serotonin receptor activation and the potential implications for cognitive and emotional processes.
Used in Controlled Substances Regulation:
As a controlled substance, 1-(2,3-dichloro-4-methoxyphenyl)ethanamine is used in the development and enforcement of regulations and policies related to the prevention of misuse and abuse of hallucinogenic and psychoactive drugs. Its classification helps ensure that research and therapeutic applications are conducted safely and responsibly, while minimizing the risks associated with non-medical use.

Check Digit Verification of cas no

The CAS Registry Mumber 1368225-72-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,8,2,2 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1368225-72:
(9*1)+(8*3)+(7*6)+(6*8)+(5*2)+(4*2)+(3*5)+(2*7)+(1*2)=172
172 % 10 = 2
So 1368225-72-2 is a valid CAS Registry Number.

1368225-72-2Upstream product

1368225-72-2Relevant academic research and scientific papers

Rational Design, Synthesis, and Pharmacological Characterization of Novel Ghrelin Receptor Inverse Agonists as Potential Treatment against Obesity-Related Metabolic Diseases

Daina, Antoine,Giuliano, Claudio,Pietra, Claudio,Wang, Junbo,Chi, Yushi,Zou, Zack,Li, Fugang,Yan, Zhonghua,Zhou, Yifan,Guainazzi, Angelo,Garcia Rubio, Silvina,Zoete, Vincent

, p. 11039 - 11060 (2018)

A new chemotype of ghrelin inverse agonists was discovered through chimeric design based on molecular scaffolds known as growth-hormone secretagogue receptor (GHSR) modulators but with divergent pharmacodynamic and pharmacokinetic properties. The structur

ASYMMETRIC UREAS AND MEDICAL USES THEREOF

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Page/Page column 47, (2012/09/10)

Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I):

ASYMMETRIC UREAS AND MEDICAL USES THEREOF

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Page/Page column 64, (2012/09/11)

Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I).

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