Journal of Medicinal Chemistry p. 11039 - 11060 (2018)
Update date:2022-08-15
Topics:
Daina, Antoine
Giuliano, Claudio
Pietra, Claudio
Wang, Junbo
Chi, Yushi
Zou, Zack
Li, Fugang
Yan, Zhonghua
Zhou, Yifan
Guainazzi, Angelo
Garcia Rubio, Silvina
Zoete, Vincent
A new chemotype of ghrelin inverse agonists was discovered through chimeric design based on molecular scaffolds known as growth-hormone secretagogue receptor (GHSR) modulators but with divergent pharmacodynamic and pharmacokinetic properties. The structur
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