136848-13-0Relevant academic research and scientific papers
Synthesis of the Two Enantiomers of 1-Chloro-1,1-difluoro-3-(p-tolylsulphonyl)propan-2-ol by Microbial Reduction of the Parent Propanone and Transformation into 3,3-Difluorotetrahydrofuran Derivatives
Arnone, Alberto,Bernardi, Rosanna,Bravo, Pierfrancesco,Cardillo, Rosanna,Ghiringhelli, Dario,Cavicchio, Giancarlo
, p. 1887 - 1892 (2007/10/02)
Both R and S enantiomers of 1-chloro-1,1-difluoro-3-(p-tolylsulphonyl)propan-2-ol were obtained with high enantioselection by microbial reduction of 1-chloro-1,1-difluoro-3-(p-tolylsulphonyl)-propan-2-one.The enantiomerically pure R-alcohol was obtained a
Intramolecular trapping of difluoroalkyl radicals by tethered olefin in the asymmetric synthesis of 2,4-disubstituted-3,3-difluorotetrahydrofurans
Cavicchio, Giancarlo,Marchetti, Valeria,Arnone, Alberto,Bravo, Pierfrancesco,Viani, Fiorenza
, p. 9439 - 9448 (2007/10/02)
Optically pure propenyl ethers of 3-sulphenyl-, 3-sulphuryl-, and 3-sulphonyl-1-chloro-1,1-difluoropropan-2-ols were submitted to radical cyclization affording, with moderate to high diastereoselectivity. 3,3-difluorotetrahydrofurans containing in 2 and 4
