136864-19-2Relevant academic research and scientific papers
Organoaluminium induced ring-opening of epoxypyranosides. IV. Synthesis and structure of γ-hydroxy-Isoleucine stereoisomers and their corresponding lactones
Inghardt, Tord,Frejd, Torbjoern,Svensson, Goeran
, p. 6469 - 6482 (1991)
Two γ-hydroxy-isoleucine stereoisomers 8 (2R, 3R, 4R), and 14 (2S, 3R, 4R) as well as their corresponding γ- lactones 9 and 15 were synthesized using a tandem. Me3Al induced opening of the epoxide and pyranoside rings of benzyl 2,3-anhydro-4-O-(tert-butyldimethylsilyl)-β-L-ribopyranoside (1). The structure of the lactone hydrochloride 9 was confirmed by an X-ray crystal structure determination.
