1369256-49-4

Upstream product

• 1420364-12-0 5-(4-chloro-3-(trifluoromethyl)phenoxy)-2-iodopyridine 
• 1420364-16-4 diethyl 2-(5-(4-chloro-3-(trifluoromethyl)phenoxy)pyridin-2-yl)malonate 
• 1420364-20-0 2-(5-(4-chloro-3-(trifluoromethyl)phenoxy)pyridin-2-yl)acetic acid 
• 1420364-07-3 5-(4-chloro-3-(trifluoromethyl)phenoxy)pyridin-2-amine 
• 1420364-02-8 5-(4-chloro-3-(trifluoromethyl)phenoxy)-2-nitropyridine 
• 6294-93-5 4-chloro-3-trifluoromethylphenol 
• 39856-50-3 5-bromo2-nitropyridine 

Relevant academic research and scientific papers

BICYCLIC PYRIMIDONE COMPOUNDS

The present invention relates to novel bicyclic pyrimidone compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.

BICYCLIC PYRIMIDONE COMPOUNDS

The present invention relates to novel bicyclic pyrimidone compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.

TRICYCLIC COMPOUNDS, PREPARATION METHODS, AND THEIR USES

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.