136927-47-4

Upstream product

• 136927-64-5 1-chloropyrrolo[1,2-a]pyrazine 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 1613164-98-9 C₂₁H₁₉N₂⁽¹⁺⁾*Br^(1-) 

Relevant academic research and scientific papers

Iridium-catalyzed asymmetric hydrogenation of pyrrolo[1,2- a ]pyrazinium salts

Highly enantioselective iridium-catalyzed hydrogenation of pyrrolo[1,2-a]pyrazinium salts has been achieved, providing a direct access to chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives with up to 95% ee. The key feature of the reaction is the addition of cesium carbonate, which increases the conversion and prohibits the racemization pathway of products.