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(4-chlorophenyl)(4-hydroxy-1,1-dioxido-2H-1,2-benzothiazin-3-yl)methanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1369377-26-3

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1369377-26-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1369377-26-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,9,3,7 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1369377-26:
(9*1)+(8*3)+(7*6)+(6*9)+(5*3)+(4*7)+(3*7)+(2*2)+(1*6)=203
203 % 10 = 3
So 1369377-26-3 is a valid CAS Registry Number.

1369377-26-3Downstream Products

1369377-26-3Relevant articles and documents

Synthesis and biological evaluation as well as in silico studies of arylpiperazine-1,2-benzothiazine derivatives as novel anti-inflammatory agents

Szcz??niak-Si?ga, Berenika M.,Wiatrak, Benita,Czy?nikowska, ?aneta,Janczak, Jan,Wiglusz, Rafal J.,Maniewska, Jadwiga

, (2021)

Novel arylpiperazine-1,2-benzothiazine derivatives have been designed and synthesized as potential anti-inflammatory agents. Their structure and properties have been studied using spectroscopic techniques (1H NMR, 13C NMR, FT-IR), MS

Synthesis of new tricyclic 1,2-thiazine derivatives with anti-inflammatory activity

Czy?nikowska, ?aneta,Maniewska, Jadwiga,Szcz??niak-Si?ga, Berenika M.,Wiatrak, Benita

, (2021)

New, tricyclic compounds containing a sulfonyl moiety in their structure, as potential safer COX inhibitors, were designed and synthesized. New derivatives have three conjugated rings and a sulfonyl group. A third ring, i.e., an oxazine, oxazepine or oxaz

Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2

Shin, Young Sup,Lee, Jun Young,Noh, Soojin,Kwak, Yoonna,Jeon, Sangeun,Kwon, Sunoh,Jin, Young-hee,Jang, Min Seong,Kim, Seungtaek,Song, Jong Hwan,Kim, Hyoung Rae,Park, Chul Min

, (2020/11/13)

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) continues to spread worldwide, with 25 million confirmed cases and 800 thousand deaths. Effective treatments to target SARS-CoV-2 are urgently needed. In the present study, we have identified a

Discovery of (2-benzoylethen-1-ol)-containing 1,2-benzothiazine derivatives as novel 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibiting-based herbicide lead compounds

Lei, Kang,Hua, Xue-Wen,Tao, Yuan-Yuan,Liu, Yang,Liu, Na,Ma, Yi,Li, Yong-Hong,Xu, Xiao-Hua,Kong, Chui-Hua

, p. 92 - 103 (2015/12/31)

A series of (2-benzoylethen-1-ol)-containing benzothiazine derivatives was synthesized, and their herbicidal activities were first evaluated. The bioassay results indicated that some of 3-benzoyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-1,1-dioxide derivatives displayed good herbicidal activity in greenhouse testing, especially, compound 4w had good pre-emergent herbicidal activities against Brassica campestris, Amaranthus retroflexus and Echinochloa crusgalli even at a dosage of 187.5 g ha-1. More importantly, compound 4w displayed significant inhibitory activity against Arabidopsis thaliana HPPD and was identified as the most potent candidate with IC50 value of 0.48 μM, which is better than the commercial herbicide sulctrione (IC50 = 0.53 μM) and comparable with the commercial herbicide mesotrione (IC50 = 0.25 μM). The structure-activity relationships was studied and provided some useful information for improving herbicidal activity. The present work indicated that (2-benzoylethen-1-ol)-containing 1,2-benzothiazine motif could be a potential lead structure for further development of novel HPPD inhibiting-based herbicides.

The interaction of new piroxicam analogues with lipid bilayers - A calorimetric and fluorescence spectroscopic study

Maniewska, Jadwiga,Szczesniak-Si Ga, Berenika,Pola, Andrzej,roda-Pomianek, Kamila,Malinka, Wieslaw,Michalak, Krystyna

, p. 1004 - 1012 (2015/02/02)

The purpose of the present paper was to assess the ability of new piroxicam analogues to interact with the lipid bilayers. The results of calorimetric and fluorescence spectroscopic experiments of two new synthesized analogues of piroxicam, named PR17 and

Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors

Sabatini, Stefano,Gosetto, Francesca,Serritella, Serena,Manfroni, Giuseppe,Tabarrini, Oriana,Iraci, Nunzio,Brincat, Jean Pierre,Carosati, Emanuele,Villarini, Milena,Kaatz, Glenn W.,Cecchetti, Violetta

, p. 3568 - 3572 (2012/06/17)

The increasing resistance to antibacterials commonly employed in the clinic and the growth of multidrug resistant strains suggest that the development of new therapeutic approaches should be of primary concern. In this context, EPIs may restore life to ol

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