1369382-20-6

Basic information

• Product Name: (Z)-1-benzyl-3-((4-methoxyphenyl)imino)indolin-2-one
• Synonyms: (Z)-1-benzyl-3-((4-methoxyphenyl)imino)indolin-2-one
• CAS NO: 1369382-20-6
• Molecular Weight: 342.397
• Mol File: 1369382-20-6.mol

Chemical Properties

• CAS DataBase Reference: (Z)-1-benzyl-3-((4-methoxyphenyl)imino)indolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-benzyl-3-((4-methoxyphenyl)imino)indolin-2-one(1369382-20-6)
• EPA Substance Registry System: (Z)-1-benzyl-3-((4-methoxyphenyl)imino)indolin-2-one(1369382-20-6)

Safety Data

• Hazardous Substances Data: 1369382-20-6(Hazardous Substances Data)

Upstream product

• 29775-73-3 1,3-dihydro-3-[(4-methoxyphenyl)imino]-2H-indol-2-one 
• 100-39-0 benzyl bromide 
• 91-56-5 indole-2,3-dione 
• 1217-89-6 1-benzylisatin 
• 104-94-9 4-methoxy-aniline 

Relevant articles and documents

Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy

Nickel-catalyzed coupling of benzyl acrylates with activated ketones and imines provides γ-butyrolactones and lactams, respectively. The benzyl alcohol byproduct released during the lactonization/lactamization event is relayed to the next cycle where it serves as the reductant for C?C bond formation. This strategy represents a conceptually unique approach to transfer-hydrogenative C?C bond formation, thus providing examples of reductive heterocyclizations where hydrogen embedded within an alcohol leaving group facilitates turnover.

Facile and highly diastereoselective synthesis of 3-aminooxindoles via AgOAc-catalyzed vinylogous Mannich reaction

A novel AgOAc-catalyzed vinylogous Mannich reaction between easily prepared imines 1 derived from isatins and trimethylsilyloxyfuran 2 (TMSOF) was developed. This method provided a facile synthetic route to get access to synthetically useful quaternary 3-aminooxindole in excellent yields (94-99%) and diastereoselectivities (>99:1).