1369424-86-1

Upstream product

• 886854-07-5 2-(2,2-dibromovinyl)-4,5-dimethoxyphenylamine 
• 536-74-3 phenylacetylene 
• 20357-25-9 6-nitroveratraldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 121-33-5 vanillin 

Downstream Products

• 1574324-33-6 5,6-dimethoxy-1-(2-nitro-4-(trifluoromethyl)phenyl)-2-(phenylethynyl)-1H-indole 
• 1574324-05-2 11,12-dimethoxy-1-phenyl-6-(trifluoromethyl)indolo[1,2-a][1,2,3]triazolo[5,1-c]quinoxaline 
• 1574323-94-6 (9,10-dimethoxyindolo[1,2-a]quinoxalin-6-yl)(phenyl)methanone 
• 1574324-19-8 5,6-dimethoxy-1-(2-nitrophenyl)-2-(phenylethynyl)-1H-indole 
• 1434160-07-2 10,11-dimethoxy-1-phenyl-6,7-dihydro-5H[1,2,3]triazolo[5',1':3,4][1,4]diazepino[1,2-a]indol-6-ol 

Relevant academic research and scientific papers

Synthesis of Azepino[1,2-a]indole-10-amines via [6+1] Annulation of Ynenitriles with Reformatsky Reagent

Lewis acid-catalyzed [6+1] annulation reactions of 2-cyano-1-propargyl- and 2-alkynyl-1-cyanomethyl-indoles with Reformatsky reagent are described. 8-Aryl, 8-alkyl-, 8-hetaryl-, 9-aryl, and 9-alkyl-azepino[1,2-a]indole amines were obtained through a 7-endo-mode cyclization of the β-aminoacrylate intermediates. The antiproliferative activity of the azepino[1,2-a]indoles analogs against the HCT-116 cells were also examined.

Efficient synthesis of pyrano[4,3-b]indol-1(5H)-ones from CO2 and alkynyl indoles promoted by a protic ionic liquid

An efficient method was developed for the synthesis of pyrano[4,3-b]indol-1(5H)-ones, which uses a protic ionic liquid [HTBD+][TFE–] as both the solvent and reaction promoter. The reactions could be efficiently carried out at atmosph