1369425-77-3

Upstream product

• 121149-70-0 1-[4-(1,1-dimethylethyl)phenyl]-2-phenylethanone 

Downstream Products

• 4210-32-6 4-tert-butyl benzonitrile 
• 1369425-86-4 (1E,3Z)-1,4-diphenyl-3-(4-tert-butylphenyl)-2-aza-1,3-butadiene 

Relevant academic research and scientific papers

Rh-Catalyzed Conversion of 3-Diazoindolin-2-imines to 5H-Pyrazino[2,3-b]indoles with Photoluminescent Properties

A rhodium-catalyzed reaction between 3-diazoindolin-2-imines and 2H-azirines, followed by treatment with a base, furnishes 5H-pyrazino[2,3-b]indoles in excellent yields. A number of functional groups tolerate the reaction conditions, and the resulting 5H-

Photocatalytic Approach for Construction of 5,6-Dihydroimidazo[2,1- A[isoquinolines and Their Luminescent Properties

A visible-light-driven photoredox reaction of tetrahydroisoquinoline with 2H-azirines is described. 4,7-Bis(4-methoxyphenyl)benzo[c][1,2,5]thiadiazole, a benzothiadiazole (BTD) derived fluorophore, is used as an organic photoredox catalyst, and the reacti

Synthesis method of azacyclopropene compound

The invention discloses a synthesis method of an azacyclopropene compound represented as the formula (II). In the presence of alkali, the compound is prepared through an intramolecularly nucleophiliccyclization reaction to an oxime ester derivative represented in the formula (I); the R1 is selected from C1-C3 alkyl groups, phenyl group, substituted phenyl groups and naphthyl groups, wherein substituent groups in the substituted phenyl groups are selected from halogens, C1-C6 alkyl groups, C1-C6 alkoxyl groups, and cyclohexyl group; the R2 is selected from hydrogen and phenyl group; the R3 isselected from hydrogen, C1-C6 alkyl groups, and halogens. The method has gentle reaction conditions, low production cost, wide application range and high yield, and may be a simple new approach for synthesis of azacyclopropene compounds having medicinal activities.

Modular 2,3-diaryl-2: H -azirine synthesis from ketoxime acetates via Cs2CO3-mediated cyclization

A modular 2H-azirine synthesis from ketoxime acetates via Cs2CO3-mediated cyclization has been developed. The reaction utilizes easily available starting materials and provides a general synthetic route to 2,3-diaryl-2H-azirines in good to excellent yields under mild conditions, which is complementary to the conventional approaches for the synthesis of 2H-azirines. A gram-scale reaction was performed to demonstrate the scale-up applicability of this synthetic method. Importantly, 2H-azirines can be efficiently converted to various azaheterocycles.

An unexpected disproportional reaction of 2H-azirines giving (1E,3Z)-2-aza-1,3-dienes and aromatic nitriles in the presence of nickel catalysts

An unprecedented nickel-catalysed disproportional reaction of 2,3-diaryl-2H-azirines forming azabutadienes and aromatic nitriles was discovered. This reaction involves the cleavage of two bonds of the 2H-azirine framework, which provides a novel type of transformation of 2H-azirines.