1369534-96-2

Basic information

• Product Name: 3-(4-bromophenoxy)Oxetane
• Synonyms: 3-(4-bromophenoxy)Oxetane
• CAS NO: 1369534-96-2
• Molecular Weight: 229.073
• Mol File: 1369534-96-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-(4-bromophenoxy)Oxetane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenoxy)Oxetane(1369534-96-2)
• EPA Substance Registry System: 3-(4-bromophenoxy)Oxetane(1369534-96-2)

Safety Data

• Hazardous Substances Data: 1369534-96-2(Hazardous Substances Data)

Usage

Type

Oxetane (cyclic ether with a three-membered ring)

Functional Group

4-bromophenoxy group

Applications

Building block in organic synthesis
Development of new materials
Pharmaceutical applications
Agrochemical applications

Unique Properties

Unique structure
Reactivity conducive to diverse applications

Safety Precautions

Handle with care
Adhere to safety guidelines
Minimize potential hazards

Upstream product

• 148430-81-3 oxetan-3-yl methane sulfonate 
• 106-41-2 4-bromo-phenol 
• 7748-36-9 oxetan-3-ol 
• 26272-83-3 oxetan-3-yl 4-methylbenzenesulfonate 
• 1369534-95-1 2-(4-bromophenoxy)-3-tosyloxy-1-propanol 
• 1369534-94-0 2-(4-bromophenoxy)-1,3-diacetoxypropane 

Downstream Products

• 1002129-40-9 C₂₁H₁₇F₃O₄ 
• 1002126-70-6 (2E,4Z)-N-(3-hydroxy-2-oxo-1,2,3,4-tetrahydro-5-quinolyl)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienamide 
• 1369534-98-4 ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate 
• 1467060-32-7 5,5-dimethyl-2-[4-(oxetan-3-yloxy)phenyl]-1,3,2-dioxaborinane 
• 1467060-33-8 6-chloro-5-[4-(oxetan-3-yloxy)phenyl]-1H-indole-3-carbaldehyde 
• 1467057-60-8 6-chloro-5-[4-(oxetan-3-yloxy)phenyl]-1H-indole-3-carboxylic acid 

Relevant articles and documents

Mild C–C Bond Formation via Lewis Acid Catalyzed Oxetane Ring Opening with Soft Carbon Nucleophiles

Mild oxetane opening by soft carbon nucleophiles has been developed for efficient C?C bond formation. In the presence of LiNTf2 or TBSNTf2 as catalyst, silyl ketene acetals were found to be effective nucleophiles to generate a wide range of highly oxygenated molecules, which are key substructure in natural products like polyketides. Furthermore, intramolecular oxetane opening by a styrene-based carbon nucleophile via a Prins-type process was also achieved with Sc(OTf)3 as catalyst, leading to efficient formation of the useful 2,3-dihydrobenzo[b]oxepine skeleton.

CATHEPSIN K INHIBITOR AND APPLICATION THEREOF

The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.

INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.