136960-85-5

Upstream product

• 136924-89-5 (+)-(2R)-8-bromo-N-<(S)-α-methylbenzyl>-2-aminotetralin 
• 136925-04-7 (+)-8-bromo-N-<(S)-α-methylbenzyl>-2(R)-propionamidotetralin 
• 117294-21-0 8-bromo-2-tetralone 
• 55116-09-1 2-bromophenylacetyl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 149526-02-3 (+)-8-bromo-N-<(S)-α-methylbenzyl>-N-propyl-2(R)-aminotetralin 

Downstream Products

• 136905-90-3 (+)-2-carbomethoxy-N-<(S)-α-methylbenzyl>-N-propyl-8(R)-amino-6,7,8,9-tetrahydro-3H-benzindole 
• 149525-98-4 (+)-2-carbamoyl-N-<(S)-α-methylbenzyl>-N-propyl-8(R)-amino-6,7,8,9-tetrahydro-3H-benzindole 
• 136925-05-8 (+)-8-<(Z)-2-azido-3-methoxy-3-oxopropenyl>-N-<(S)-α-methylbenzyl>-N-propyl-2(R)-aminotetralin 

Relevant academic research and scientific papers

Novel 2-substituted tetrahydro-3H-benz[e]indolamines: Highly potent and selective agonists acting at the 5-HT(1A) receptor as possible anxiolytics and antidepressants

The synthesis of (+)-(R)-2-cyano-N,N-dipropyl-8-amino-6,7,8,9-tetrahydro- 3H-benz[e]indole [(R)-14, U92016A], a potent 5-HT(1A) agonist, and related analogs is described. In vitro binding studies show that the (R)-enantiomers of this series possess the hi