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(1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]octan-6-ol, commonly known as tropane, is a bicyclic organic compound belonging to the class of tropane alkaloids. It has a molecular formula of C8H15NO and is derived from plants such as nightshades and belladonna. Tropane exhibits psychoactive and toxic effects, making it a compound of interest in both medicinal and controlled substance contexts.

1369774-29-7

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1369774-29-7 Usage

Uses

Used in Pharmaceutical Industry:
(1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]octan-6-ol is used as an active pharmaceutical ingredient for the development of drugs with various therapeutic applications. Its ability to act as a competitive antagonist of the muscarinic acetylcholine receptors allows it to induce physiological effects such as pupil dilation, dry mouth, and in some cases, hallucinations. This makes it a valuable component in medications targeting specific conditions.
Used in Controlled Substances:
Due to its psychoactive effects and potential for abuse, (1R,5S,6R)-Rel-8-Azabicyclo[3.2.1]octan-6-ol has been listed as a controlled substance in some countries. Its regulation is necessary to prevent misuse and ensure that it is used safely and appropriately within the medical field.

Check Digit Verification of cas no

The CAS Registry Mumber 1369774-29-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,9,7,7 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1369774-29:
(9*1)+(8*3)+(7*6)+(6*9)+(5*7)+(4*7)+(3*4)+(2*2)+(1*9)=217
217 % 10 = 7
So 1369774-29-7 is a valid CAS Registry Number.

1369774-29-7Relevant academic research and scientific papers

Syntheses of (-)-pelletierine and (-)-homopipecolic acid

Chiou, Wen-Hua,Chen, Guei-Tang,Kao, Chien-Lun,Gao, Yu-Kai

, p. 2518 - 2520 (2012/04/23)

Enantiomeric syntheses of (-)-homopipecolic acid and (-)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer-Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. The Royal Society of Chemistry 2012.

Efficient enantioselective synthesis of piperidines through catalytic asymmetric ring-opening/cross-metathesis reactions

Cortez, G. Alex,Schrock, Richard R.,Hoveyda, Amir H.

, p. 4534 - 4538 (2008/09/17)

Mo the better! Chiral Mo complexes promote highly efficient asymmetric ring-opening/cross-metathesis reactions that afford functionalized piperidines in high E:Z selectivity and enantiomeric purity (see scheme for example; TBS = tert-butyldimethylsilyl).

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