1369810-85-4

Basic information

• Product Name: tert-butyl (3R,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate
• Synonyms: tert-butyl (3R,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate
• CAS NO: 1369810-85-4
• Molecular Weight: 427.541
• Mol File: 1369810-85-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (3R,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3R,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate(1369810-85-4)
• EPA Substance Registry System: tert-butyl (3R,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate(1369810-85-4)

Safety Data

• Hazardous Substances Data: 1369810-85-4(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 177420-29-0 (3R,4R)-tert-butyl 3,4-bis(benzyloxy)-5-methylenepiperidine-1-carboxylate 
• 1369810-92-3 (3R,4S,5R)-tert-butyl 4,5-bis(benzyloxy)-3-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate 
• 1369810-93-4 (3S,4S,5R)-tert-butyl 4,5-bis(benzyloxy)-3-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate 
• 169105-89-9 isofagomine 
• 275363-98-9 (3R,4R,5S)-3,4-dihydroxy-5-hydroxymethylpiperidine 
• 1369810-86-5 (2R,3R)-2,3-bis(benzyloxy)-4-((tert-butoxycarbonylamino)methyl)pent-4-enyl methanesulfonate 

Relevant articles and documents

Aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a versatile strategy towards synthesis of isofagomine and related biologically important azasugars

Synthesis of isofagomine has been achieved by implementation of aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a key step. The above rearrangement has also been utilized in the synthesis of biologically important polyhydroxylated piperidine frameworks such as isogalactofagomine, ent-isogalactofagomine and their analogues and some other azasugars as glycosidase inhibitors. The Royal Society of Chemistry 2012.