136985-48-3Relevant articles and documents
The synthesis and stereochemistry of new 2-substituted 4-thiazolidine acetic acids
Martens,Kintscher,Arnold
, p. 7029 - 7036 (1991)
Reaction of isopropylidene-protected β-homopenicillamine 2 with various aldehydes leads to a number of new 2-monosubstituted 4-thiazolidine acetic acids 4. Thiazolidines 4 are formed with high diastereoselectivity. Assignment of configuration is made by NMR-analysis. The diastereomeric pure compound 4 possess unstable chiral centers in position 2 and undergo rapid epimerisation in solution at higher temperatures.