1369853-06-4

Upstream product

• 100-39-0 benzyl bromide 
• 40619-73-6 2-(1-benzyl-5-methoxy-1H-indol-3-yl)ethylamine 
• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 1369852-97-0 (E)-N-{2-[1-benzyl-2-(3-hydroxyprop-1-en-1-yl)-5-methoxy-1H-indol-3-yl]ethyl}-2,2,2-trifluoroacetamide 
• 79-22-1 methyl chloroformate 
• 1369852-86-7 N-[2-(1-benzyl-2-iodo-5-methoxy-1H-indol-3-yl)ethyl]-2,2,2-trifluoroacetamide 
• 1369852-63-0 N-[2-(1-benzyl-5-methoxy-1H-indol-3-yl)ethyl]-2,2,2-trifluoroacetamide 

Downstream Products

• 1369853-11-1 1-{9-benzyl-6-methoxy-1-vinyl-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl}-2,2,2-trifluoroethanone 

Relevant academic research and scientific papers

Synthetic approaches to highly functional -carboline building blocks via allylic amidation

A new, straightforward synthesis of highly functional -carboline building blocks is presented that makes use of allylic amidation methodology. The products obtained carry a terminal double bond as well as an easy-to-deprotect amide, which make them perfectly suitable for further functionalization. The use of the trifluoroacetamide group is exploited in a dual fashion; it acts as a protecting group and functions as the nucleophile for the allylic amidation reaction. Georg Thieme Verlag Stuttgart New York.