136992-57-9

Upstream product

• 128828-95-5 (1R,3R)-3-(4-Benzyloxy-butyl)-1-((1S,2R)-3-benzyloxy-1,2-dihydroxy-propyl)-8-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 54639-89-3 (2-bromo-3-methoxyphenyl)acetic acid 
• 128828-86-4 2-bromo-1-(bromomethyl)-3-methoxybenzene 
• 38197-43-2 2-bromo-3-methylanisole 
• 159255-57-9 (1R,3R)-3-(4-Benzyloxy-butyl)-1-((4R,5R)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-8-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 136992-55-7 methyl 7-benzy loxy-2-(2-bromo-3-methoxyphenyl)-3-hydroxyheptanoate 
• 159255-55-7 methyl 7-benzyloxy-2-(2-bromo-3-methoxyphenyl)-3-oxoheptanoate 
• 128828-90-0 6-benzyloxy-1-(2-bromo-3-methoxyphenyl)-2-hexanone 
• 128828-88-6 methyl (2-bromo-3-methoxyphenyl)acetate 
• 128828-87-5 (2-bromo-3-methoxyphenyl)acetonitrile 
• 78999-24-3 5-benzyloxy-1-pentanal 
• 159255-56-8 6-benzyloxy-1-(2-bromo-3-methoxyphenyl)-2,2-dimethoxyhexane 
• 128828-93-3 (E)-6-benzyloxy-1-<2-<(4S,5R)-5-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methoxyphenyl>-2-methoxy-1-hexene 
• 128828-94-4 6-benzyloxy-1-<2-<(4S,5R)-5-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl>-3-methoxyphenyl>-2-hexanone 

Downstream Products

• 136992-58-0 (1R,3R)-tert-butyl 3-(4-benzyloxybutyl)-8-methoxy-1-methoxymethoxymethyl-3,4-dihydro-2(1H)-isoquinolinecarboxylate 

Relevant academic research and scientific papers

Synthetic studies on quinocarcin and its related compounds. 2. Synthesis of an enantiomeric pair of the ABC ring system of quinocarcin

An enantiomeric pair of the ABC ring system (5 and ent-5) of quinocarcin (1), a potent antitumor antibiotic, was synthesized in> 95%.

CHIRAL SYNTHESIS OF THE ABC-RING SYSTEM OF QUINOCARCIN

Stereoselective synthesis of an enantiomeric pair of the ABC-ring system of quinocarcin(1), a notable antitumor antibiotic, could be achieved in >95percentee by utilizing each enantiomer of 4-O-benzyl-2,3-O-isopropylidene-threose as a chiral auxiliary and